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Alexander van Akkooi

Alexander CJ van Akkooi MD, PhD

Melanoma and Soft Tissue Sarcoma Surgeon, Netherlands Cancer Institute – Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands

Dr. Alexander van Akkooi is a board-certified surgical oncologist specializing in melanoma and sarcoma and practicing at the Netherlands Cancer Institute – Antoni van Leeuwenhoek (NCI-AVL) in Amsterdam. Dr van Akkooi is the current chairman of the Dutch Melanoma Tumor Focus Group (TFG) and the current chairman of the EORTC (European Organization for Research and Treatment of Cancer) Melanoma Group. He is the head of the NCI-AVL Skin Cancer and Melanoma Unit. Dr van Akkooi has published over 100 peer-reviewed papers in high-impact journals, including NEJM, Lancet, Lancet Oncology, Cell, Nature Medicine, among others, and has presented at numerous international meetings. He is a member of the European Society for Medical Oncology, Society for Melanoma Research, and American Society of Clinical Oncology.

Dr. van Akkooi was awarded his medical degree from Erasmus University in Rotterdam. He was a resident in general surgery at Maasstad Ziekenhuis in Rotterdam, and underwent residency training in surgical oncology at NCI-AVL and Erasmus MC Cancer Institute. His PhD was awarded cum laude from Erasmus University.

Recent Contributions to PracticeUpdate:

  1. Update on Tolerability and Overall Survival in COLUMBUS: Encorafenib + Binimetinib vs Vemurafenib or Encorafenib in BRAF V600–Mutant Melanoma
  2. Potential Detrimental Effect of Antibiotics on Clinical Outcomes in the Setting of Immune-Checkpoint Blockade
  3. DCE-MRI Perfusion Predicts Pseudoprogression in Metastatic Melanoma Treated With Immunotherapy
  4. The Potential Development of PD-L1 as a Biomarker in Advanced Melanoma
  5. An Open-Source Automated Tumor-Infiltrating Lymphocyte Algorithm for Prognosis in Melanoma
  6. Adjuvant Ipilimumab vs High-Dose Interferon Alfa-2b for Resected High-Risk Melanoma
  7. Survival Outcomes After Metastasectomy in Melanoma Patients Categorized by Response to Checkpoint Blockade
  8. Glucocorticoid-Induced TNF Receptor–Related Protein Agonist Alone or With Nivolumab for Advanced Solid Tumors
  9. A Systematic Literature Review and Network Meta-Analysis of Effectiveness and Safety Outcomes in Advanced Melanoma
  10. Updates on T-VEC in the Management of Melanoma

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