We have detected that you are using an Ad Blocker.
PracticeUpdate is free to end users but we rely on advertising to fund our site. Please consider supporting PracticeUpdate by whitelisting us in your ad blocker.
We have sent a message to the email address you have provided, . If this email is not correct, please update your settings with your correct address.
The email address you provided during registration, , does not appear to be valid. Please update your settings with a valid address before to continue using PracticeUpdate.
Please provide your AHPRA Number to ensure that you are given the correct level of access to our site.

Expert Opinion / Cases · February 20, 2020

Widely Metastatic Prostate Cancer at Diagnosis

Written by
Jeffrey J. Tosoian MD, MPH


Additional Info

Disclosure statements are available on the authors' profiles:

Discuss This item Follow

No comments yet, be the first to start the discussion!

  • Comment deleted by Moderator.
  • Noureddine Benjaafar

    Either ADT + Docetaxel and ADT + Abiraterone is valid in this case

  • GANDA Oumarou Sanda

    ADT+ abiraterone Fractioned radiotherapy if bone pain

  • Hisashi Matsushima

    There is no obvious organ metastasis in this case. Standard ADT+ abiraterone + predonisone should be preferred.

  • Radoslav Mangaldzhiev

    If he was fit I would recommend ADT + DOC in first choice due to high volume disease.

  • Judy Hiemenga

    And please don’t omit an early consult in Cancer Genetics.

  • Huan Wang

    ADT+DOC or ADT+Abiraterone is a reasonable treatment choice based on CHARTTED and LATITUDE study. The patient is young with high volume disease, genetic testing should be recommend strongly.

  • Samba Thiapato  Faye

    In our daily practice, we do ADT + Docetaxel if the patient is fit... If he isn't it, we use ADT only + Prednisone.

  • Ismail Abdelhafeez

    ADT + DOC , pending on response post chemo, may advise Lutitium 177 in a clinical trial!

  • Comment deleted by User.
  • Ofobuike Okani

    I would start with ADT+DOC + bisphosphonate if PS is <2 and GFR is >60. If PS is >2, would start with Abiraterone+Pred and add a bisphosphonate if GFR>60.

  • Oct 22, 2021

    Pending Moderator approval.

Further Reading