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Published in Oncology

Expert Opinion / Interview · May 23, 2013

Trends in the Treatment of Chemotherapy-Induced Peripheral Neuropathy

Written by
Charles L Loprinzi MD


Additional Info

  1. Rao RD, Michalak JC, Sloan JA, et al. Efficacy of gabapentin in the management of chemotherapy-induced peripheral neuropathy: a phase 3 randomized, double-blind, placebo-controlled, crossover trial (N00C3). Cancer. 2007;110(9):2110-2118.

  2. Smith EM, Pang H, Cirrincione C, et al. Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial. JAMA. 2013;309(13):1359-1367.

  3. Durand JP, Deplanque G, Montheil V, et al. Efficacy of venlafaxine for the prevention and relief of oxaliplatin-induced acute neurotoxicity: results of EFFOX, a randomized, double-blind, placebo-controlled phase III trial. Ann Oncol. 2012;23(1):200-205.

  4. Barton DL, Wos EJ, Qin R, et al. A double-blind, placebo-controlled trial of a topical treatment for chemotherapy-induced peripheral neuropathy: NCCTG trial N06CA. Support Care Cancer. 2011;19(6):833-841.

  5. Smith TJ, Coyne PJ, Parker GL, et al. Pilot trial of a patient-specific cutaneous electrostimulation device (MC5-A Calmare®) for chemotherapy-induced peripheral neuropathy. J Pain Symptom Manage. 2010;40(6):883-891.

  6. Storey DC, LA. Boyle, D. Scott, et al. Topical menthol: a novel intervention that improved chemotherapy induced peripheral neuropathy (CIPN) related pain and physical function. Support Care Cancer. 2011;19(suppl 2):S158.

  7. Wong GY, Michalak JC, Sloan JA, et al. A phase III double blinded, placebo controlled, randomized trial of gabapentin in patients with chemotherapy-induced peripheral neuropathy: A North Central Cancer Treatment Group study. J Clin Oncol. 2005;23(suppl 16):8001.

Further Reading