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The Proposed 9th Edition TNM Classification of Lung Cancer
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- This article from the International Association for the Study of Lung Cancer outlines proposed updates to the classification nomenclature for lung cancer, including non–small cell lung cancer, small cell lung cancer, and bronchopulmonary carcinoid tumors. Drawing on a growing database, these updates focus on the TNM system, which categorizes cancer according to the features of primary tumor extent (T), lymph node involvement (N), and distant metastases (M).
- The highlights include substantial changes to subcategories within the N and M components, which have implications for treatment strategies. These changes will be adopted by the American Joint Committee on Cancer and Union for International Cancer Control in January 2025.
abstract
This abstract is available on the publisher's site.
Access this abstract now Full Text Available for ClinicalKey SubscribersA universal nomenclature of the anatomic extent of lung cancer has been critical for individual patient care as well as research advances. As progress occurs, new details emerge that need to be included in a refined system that aligns with contemporary clinical management issues. The 9th edition TNM classification of lung cancer, which is scheduled to take effect in January of 2025, addresses this need. It is based on a large international database, multidisciplinary input and extensive statistical analyses. Key features of the 9th edition include validation of the significant changes in the T component introduced in the 8th edition, subdivision of N2 after exploration of fundamentally different ways of categorizing the N component, and further subdivision of the M component. This has led to reordering of the TNM combinations included in stage groups, primarily involving stage groups IIA, IIB, IIIA and IIIB. This paper summarizes the analyses and revisions for the TNM classification of lung cancer to familiarize the broader medical community and facilitate implementation of the 9th edition system.
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The Proposed 9th Edition TNM Classification of Lung Cancer
Chest 2024 Jun 15;[EPub Ahead of Print], FC Detterbeck, GA Woodard, AS Bader, S Dacic, MJ Grant, HS Park, LT TanoueFrom MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.