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The COVID-19 pandemic has forced various changes in healthcare, and changes that reduce exposure for both patients and healthcare personnel are important to consider. The authors of this viewpoint discuss the use of tenecteplase instead of alteplase for acute ischemic stroke treatment. Tenecteplase is administered as a single 5-second intravenous bolus, as opposed to the 1-hour infusion time for alteplase. The article includes practical points for hospitals to consider for transitioning to the use of tenecteplase.
Tenecteplase thrombolysis may be a good alternative to alteplase in the context of the COVID-19 pandemic.
– Codrin I. Lungu, MD
This abstract is available on the publisher's site.
Measures to reduce emergency department staff exposure to the severe acute respiratory syndrome coronavirus 2 have focused on screening and use of personal protective equipment. Reducing the time and intensity of interactions with individuals with known or suspected cases of coronavirus disease 2019 (COVID-19) is also desirable, insofar as such reductions do not compromise the quality or outcomes of care. The situation of an acute stroke emergency is a particularly vulnerable situation for exposure and transmission, since a substantial proportion of patients are unable to provide a history to screen them out for COVID-19.