We have detected that you are using an Ad Blocker. PracticeUpdate is free to end users but we rely on advertising to fund our site. Please consider supporting PracticeUpdate by whitelisting us in your ad blocker.
We have sent a message to the email address you have provided, . If this email is not correct, please update your settings with your correct address.
The email address you provided during registration, , does not appear to be valid. Please update your settings with a valid address before to continue using PracticeUpdate.
Welcome to PracticeUpdate! We hope you are enjoying access to a selection of our top-read and most recent articles. Please register today for a free account and gain full access to all of our expert-selected content.
You can find your saved items on your dashboard, in the "saved" tab.
You've recommended your first item
Your recommendations help us improve our content suggestions for you and other PracticeUpdate members.
You've subscribed to your first topic alert
What does that mean?
Each day, we'll check to see if new items have been published to the topics you're subscribed to, and we'll send you one email with all of the new items from that day.
We'll keep all topic alert notifications available on your dashboard for 30 days, to make sure you don't miss anything.
Lastly, whenever you have unread items in the topics you've subscribed to, the "Alerts" icon will light up in the main menu. Just click on the bell to see your five most-recent, unread notifications.
The authors of this review summarize current literature regarding prothrombotic coagulopathy and thrombotic complications in patients with SARS-CoV-2 infection. They discuss these issues as related to acute management of cerebrovascular accidents in this patient population, noting that the risk of stroke associated with SARS-CoV-2 has been estimated to be between 0.9% and 4.5%. They recommend thigh-high intermittent pneumatic compression in addition to other deep venous thrombosis prophylaxis for all critically ill patients with COVID-19 who do not have other contraindications for compression.
For patients presenting with acute ischemic stroke and COVID-19, the authors did not find additional contraindications to thrombolysis beyond the normal guidelines. They recommend initiating thromboprophylaxis as soon as the 24-hour interval has passed because these patients are at high risk for additional thromboses. Finally, they note that critically ill patients with COVID-19 should be considered for increased dosing of thromboprophylaxis because the underlying infection is associated with a prothrombotic state.
– Kyle Binder, MD
This abstract is available on the publisher's site.
In the rapidly evolving COVID-19 pandemic, many patients presenting with acute ischemic stroke may be potentially infected with the Severe Acute Respiratory Syndrome Coronavirus (SARS CoV-2) agent. As stroke patients are often unable to give an adequate history of preceding COVID-19 symptoms, all stroke patients in areas with high prevalence of community transmission should be considered potential cases. Observational studies have suggested an increased tendency for thrombotic events in patients infected with SARS CoV- 2. These events include cryptogenic strokes with large vessel occlusion predominance [1, 2], deep-vein thrombosis (DVT) and pulmonary embolism (PE) [3-5]. Acute ischemic stroke is associated with rates of DVT as high as 50% , in the absence of COVID-19. Although acute stroke management algorithms in the COVID-19 pandemic have been proposed [7-9], it is as important to review updated information on thromboprophylaxis during the COVID-19 pandemic for acute stroke patients and to develop practice guidance for the prevention of DVT and PE in this population.