We have detected that you are using an Ad Blocker. PracticeUpdate is free to end users but we rely on advertising to fund our site. Please consider supporting PracticeUpdate by whitelisting us in your ad blocker.
We have sent a message to the email address you have provided, . If this email is not correct, please update your settings with your correct address.
The email address you provided during registration, , does not appear to be valid. Please update your settings with a valid address before to continue using PracticeUpdate.
Welcome to PracticeUpdate! We hope you are enjoying access to a selection of our top-read and most recent articles. Please register today for a free account and gain full access to all of our expert-selected content.
You can find your saved items on your dashboard, in the "saved" tab.
You've recommended your first item
Your recommendations help us improve our content suggestions for you and other PracticeUpdate members.
You've subscribed to your first topic alert
What does that mean?
Each day, we'll check to see if new items have been published to the topics you're subscribed to, and we'll send you one email with all of the new items from that day.
We'll keep all topic alert notifications available on your dashboard for 30 days, to make sure you don't miss anything.
Lastly, whenever you have unread items in the topics you've subscribed to, the "Alerts" icon will light up in the main menu. Just click on the bell to see your five most-recent, unread notifications.
This Italian single-center prospective study examined the effects of the COVID-19 pandemic on the clinical features and management of ST-segment–elevation myocardial infarction (STEMI) by comparing data for 26 patients who presented during the study period during the pandemic with data from patients who presented during analogous periods in 2018 and 2019. Of the 26 patients who presented with STEMI during the pandemic in 2020, 26.9% tested positive for COVID-19. No differences in medical therapy was found between the pandemic cohort and historical cohort. Compared with the historical cohort, the pandemic cohort had a longer median time between symptom onset and hospital admission (15.0 and 2.0 hours, respectively). Additionally, the proportion of patients with late-presentation STEMI was significantly higher in 2020 versus the historical cohort. All patients in the historical cohort underwent percutaneous coronary intervention (PCI), compared with 80.8% of patients in 2020 (P = .06).
Although this study found many similarities between patients presenting with STEMI in 2020 and a historical cohort, patients who experienced STEMI in 2020 waited longer to seek hospital care, and there is a need to better understand how to manage the effects of the COVID-19 pandemic and possible future pandemics on patients with other conditions.
This abstract is available on the publisher's site.
Coronavirus disease 2019 (COVID-19) pandemic has led to a fast and radical transformation in social, economic, and healthcare networks. COVID-19 outbreak may thus have profound indirect consequences on clinical presentation and management of patients with ST-segment-elevation myocardial infarction (STEMI). Aim of this study was to assess clinical features of patients with STEMI during COVID-19 pandemic.
This single-center, prospective study from a regional public service healthcare hub in Milan included all consecutive patients with STEMI admitted to our institute from February 21 to April 1, 2020 (during COVID-19 pandemic). These patients were compared with a historical cohort of patients admitted for STEMI during the analogous time period (February 21 to April 1) in 2018 and 2019, in terms of time from symptoms onset to hospital admission, clinical characteristics, and in-hospital outcomes.
A total of 26 patients were admitted for STEMI during the study period, and 7 (26.9%) of these patients tested positive for severe acute respiratory syndrome coronavirus 2. On admission, medical therapy, including angiotensin-converting enzyme inhibitors and angiotensin receptor blockers use, was similar between cohorts. Median (interquartile range) time from symptoms onset to hospital admission was significantly longer in 2020 as compared to the historical cohort (15.0 [2.0-48.0] versus 2.0 [1.0-3.0] hours; P<0.01). A higher proportion of patients presenting with late presentation STEMI was observed in 2020 compared with the historical cohort (50.0% versus 4.8%; P<0.01). Primary percutaneous coronary intervention resulted indicated in 80.8% of patients in 2020 compared with 100% in the historical cohort (P=0.06). In-hospital death, thromboembolism, mechanical ventilation, or hemodynamic decompensation needing inotropic or mechanical support were similar between years.
These preliminary results from a cardiovascular regional public service healthcare hub demonstrate a significantly longer time from symptoms onset to hospital admission among patients with STEMI during COVID-19 pandemic compared with the same time period in the previous 2 years.
ST-Segment-Elevation Myocardial Infarction During COVID-19 Pandemic: Insights From a Regional Public Service Healthcare Hub
Circ Cardiovasc Interv 2020 Aug 01;13(8)e009413, M Gramegna, L Baldetti, A Beneduce, L Pannone, G Falasconi, F Calvo, V Pazzanese, S Sacchi, M Pagnesi, F Moroni, S Ajello, G Melisurgo, E Agricola, PG Camici, AM Scandroglio, G Landoni, F Ciceri, A Zangrillo, AM Cappelletti