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Avindra Nath MD
Avindra Nath MD Associate Editor
Nina Schor MD, PhD
Nina F. Schor MD, PhD Advisory Board
Argye Hillis MD, MA
Argye Elizabeth Hillis MD, MA Associate Editor
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Published in Neurology

Expert Opinion / Commentary · March 17, 2015

Should the Ketogenic Diet be Considered When All Else Fails in Infants and Children With Super Refractory Status Epilepticus?

Michael Cardamone MD
Preena Uppal MBBS, MD

 

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Additional Info

  1. Shorvon SD, Ferlisi M. The treatment of super-refractory status epilepticus: a critical review of available therapies and a clinical treatment protocol. Brain. 2011;134(Pt 10):2802-2818.
  2. Freeman JM, Kossoff EH. Ketosis and the ketogenic diet, 2010: advances in treating epilepsy and other disorders. Adv Pediatr. 2010;57(1):315-329.
  3. Nabbout R, Mazzuca M, Hubert P, et al. Efficacy of ketogenic diet in severe refractory status epilepticus initiating fever induced refractory epileptic encephalopathy in school age children (FIRES). Epilepsia. 2010;51(10):2033-2037.

  4. Bleck TP. High-dose pentobarbital treatment of refractory status epilepticus: a meta-analysis of published studies. Epilepsia. 1992;33:5.

  5. Dulac O, Takahashi T. Status epilepticus. Handb Clin Neurol. 2013;111:681-689.
  6. Wheless JW. Treatment of refractory convulsive status epilepticus in children: other therapies. Semin Pediatr Neurol. 2010;17(3):190-194.

  7. Cobo N, Sankar R, Murata KK, Sewak SL, Kezele MA, Matsumoto JH. The ketogenic diet as broad-spectrum treatment for super-refractory staus epilepticus: challenges in implementation in the pediatric and neonatal intensive care units. J Child Neurol. 2015;30(2):259-256.

  8. Selter JH, Turner Z, Doerrer SC, Kossoff EH. Dietary and medication adjustments to improve seizure control in patients treated with the ketogenic diet. J Child Neurol. 2015;30(1):53-57.

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