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Expert Opinion / Commentary · October 21, 2015

Risky? Active Surveillance in Black Men With Low-Risk Prostate Cancer

Written by
Debasish Sundi MD
Edward M. Schaeffer MD, PhD


Additional Info

  1. Cooperberg MR, Carroll PR. Trends in management for patients with localized prostate cancer, 1990-2013. JAMA. 2015;314(1):80-82.
  2. Dall’Era M, Albertsen PC, Bangma C, et al. Active surveillance for prostate cancer: a systematic review of the literature. Eur Urol. 2012;62(6):976-983.
  3. Sundi D, Ross A, Humphreys E, et al. African American men with very low risk prostate cancer exhibit adverse oncologic outcomes after radical prostatectomy. Should active surveillance still be an option for them? J Clin Oncol. 2013;31(24):2991-2997.
  4. Ha Y-S, Salmasi A, Karellas M, et al. Increased incidence of pathologically nonorgan confined prostate cancer in African-American men eligible for active surveillance. Urology. 2013;81(4):831-835.
  5. Pietzak EJ, Van Arsdalen K, Patel K, et al. Impact of race on selecting appropriate patients for active surveillance with seemingly low-risk prostate cancer. Urology. 2015;85(2):436-441.
  6. Iremashvili V, Soloway MS, Rosenberg DL, et al. Clinical and demographic characteristics associated with prostate cancer progression in patients on active surveillance. J Urol. 2012;187(5):1594-1599.
  7. Abern MR, Bassett MR, Tsivian M, et al. Race is associated with discontinuation of active surveillance of low-risk prostate cancer: Results from the Duke Prostate Center. Prostate Cancer Prostatic Dis. 2013;16(1):85-90.
  8. Sundi D, Faisal FA, Trock BJ, et al. Reclassification rates are higher among African American men than Caucasians on active surveillance. Urology. 2015;85(1):155-160.
  9. Faisal FA, Sundi D, Cooper JL, et al. Racial disparities in oncologic outcomes after radical prostatectomy: long-term follow-up. Urology. 2014;84(6):1434-1441.
  10. Mahal B, Aizer A, Ziehr DR, et al. Racial disparities in prostate cancer-specific mortality in men with low-risk prostate cancer. Clin Genitourin Cancer. 2014;12(5):e189-e195.
  11. Schreiber D, Levy EB, Schwartz D, et al. Impact of race in a predominantly African-American population of patients with low/intermediate risk prostate cancer undergoing radical prostatectomy within an equal access care institution. Int Urol Nephrol. 2014;46(10):1941-1946.
  12. Powell IJ, Dyson G, Land S, et al. Genes associated with prostate cancer are differentially expressed in African American and European American men. Cancer Epidemiol Biomarkers Prev. 2013;22(5):891-897.
  13. Yamoah K, Johnson MH, Choeurng V, et al. Novel biomarker signature that may predict aggressive disease in African American men with prostate cancer. J Clin Oncol.2015;33(25):2789-2796.
  14. Schreiber D, Chhabra A, Rineer J, et al. A population-based study of men with low-volume low-risk prostate cancer: does African-American race predict for more aggressive disease? Clin Genitourin Cancer. 2015;13(4):e259-e264.
  15. Jalloh M, Myers F, Cowan JE, et al: Racial variation in prostate cancer upgrading and upstaging among men with low-risk clinical characteristics. Eur Urol. 2015;67(3):451-457.

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