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Expert Opinion / Cases · November 21, 2016

New Hormone Receptor Positive Breast Cancer While on Endocrine Therapy

Written by
Sameer Nasir MD

 

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  • Beata Kania-Zembaczyńska

    Nov 25, 2016

    New hormone positive breast cancer
    Mastectomy with slnd,and hormonotherapy -tamoxifen

  • Guy Lesec

    Nov 26, 2016

    The phenotype is close to the previous one, but we do not know if the grade is different and whether it is a luminal A or B. (KI 67?). However, recurrences are often more evolutive (3 cm): therefore, it is necessary to propose a total matectomy with axillary dissection, with the aid of a colored and radioactive tracer, but completing by a wider dissection given the cicatrational state of the lymphatic path. The other decisions depend on the new staging. A new-generation hormone therapy is in any case indicated

  • nagib khoury

    Nov 26, 2016

    most probably a new breast cancer,developped in a different quandrant..if us of the axilla is negative consider total mastectomy because of the size of the tumor.Breast irradiation can be added . post op palbociclib and fulvestrant is one option 

  • Nguyen Minh Tinh

    Nov 27, 2016

    I think this is recurrent Breast Cancer
    I recomment surgical for breast not axilla LND
    May be adjuvant RT 
    Systemic thẻapy: chemo follow Hormon

  • Oda Abushaban

    Dec 25, 2016

    This is recurrence B C need for MRM with axilla ,adjuvant RT and Tomoxfen +follow up

  • pramod kumar julka

    Feb 08, 2017

    it is new breast cancer  Mastectomy with sentinal lymph node dissection .genetic assay oncotype dx or endopredict may be done if low risk  PALBOCICLIB &FULVUSTRANT MAY BE GIVEN OTHERWISE CHEMOTHERAPY

  • Juan Rodriguez Agostini

    Feb 09, 2017

    I think it is a reccurrence from initial tumor. The therapeutic option is total mastectomy + SLNB (re-mapping) + Axillary clearance if SLN is positive. Radiation may be omitted if we do a total mastectomy. Systemic treatment: hormonal therapy with another AI (exemestane for example)

  • mouna kairouani

    Feb 19, 2017

    I think it is a recurrent breast cancer. I propose mastectomy with axillary dissection. The patient has already received radiotherapy. This is a secondary endocrine resistance with a relapse on the third year of hormone therapy. It is important to precise the ki 67 and score of oncotype dx for decision

  • Muhammad Jawaid Akhter Malick

    May 26, 2018

    In my opinion this is recurrent disease. Mastectomy +Ald. Then my look for recurrence score. Manage according to the recurrence rate, second line hormone therapy + xrt to axila + sup.clav. If high risk then chemotherapy followed by above.

  • pramod kumar julka

    May 28, 2018

    This is a new lesion. This may be treated by breast conservation surgery and put on hormones.

  • pramod kumar julka

    May 28, 2018

    This is a new lesion. This may be treated by breast conservation surgery and put on hormones.

  • Apr 19, 2024

    Pending Moderator approval.
    Delete

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