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Published in Primary Care

Expert Opinion / My Approach · October 22, 2019

MY APPROACH to Choosing a Direct Oral Anticoagulant (DOAC)

Written by
Allison E Burnett PharmD, PhC, CACP
Emily A Shephard MD

 

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Additional Info

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  2. January CT, Wann LS, Calkins H, et al. 2019 AHA/ACC/HRS focused update of the 2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation. Circulation. 2019;140(2):e125-e151.
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  4. Kushner M, Choi Y, Eisenberg R, et al. Efficacy and safety of direct oral factor Xa inhibitors compared with warfarin in patients with morbid obesity: a single-centre, retrospective analysis of chart data. Lancet Haematol. 2019;6(7):e359-e365.
  5. McBane Ii R, Loprinzi CL, Ashrani A, et al. Apixaban and dalteparin in active malignancy associated venous thromboembolism. Thromb Haemost. 2017;117(10):1952-1961.
  6. Raskob GE, van Es N, Verhamme P, et al. Edoxaban for the treatment of cancer-associated venous thromboembolism. N Engl J Med. 2018; 378(7):615-624.
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  8. Streiff MB, Holmstrom B, Angelini D, et al. NCCN clinical practice guidelines in oncology. Cancer-associated venous thromboembolic disease, version 1.2019. Published February 28, 2019.
  9. Steinberg BA, Shrader P, Thomas L, et al. Off-label dosing of non-vitamin K antagonist oral anticoagulants and adverse outcomes: the ORBIT-AF II registry. J Am Coll Cardiol. 2016;68(24):2597-2604.
  10. Trujillo-Santos J, Di Micco P, Dentali F, et al. Real-life treatment of venous thromboembolism with direct oral anticoagulants: The influence of recommended dosing and regimens. Thromb Haemost. 2017;117(2):382-389.
  11. Young AM, Marshall A, Thirlwall J, et al. Comparison of an oral factor Xa inhibitor with low molecular weight heparin in patients with cancer with venous thromboembolism: results of a randomized trial (SELECT-D). J Clin Oncol. 2018;(36)20:2017-2023.

Disclosure statements are available on the authors' profiles:

Allison Burnett PharmD, PhC, CACP

Emily Shephard MD

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