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Expert Opinion / Cases · November 27, 2019

Multifocal Lobular in Young Pre-menopausal Woman—Treatment Opinions?

Trish O’Brien

 

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  • Saiji Nageshwaran

    Could also give 4x 2 weekly dose dense Paclitaxel instead of weekly. Also consider BRCA and risk reduction contralateral if not already done.


  • Isabel Pimentel

    BRCA status? I would consider her for a clinical trial with cdKi in the adjuvant setting.


  • Stefan Todorov

    Neoadjuvant cdk4/6 inhibitor plus aromataseinhibitor?


  • Carlos Calderon

    The ovarian ablation, premature menopause may be associated with long-term health effects, including cardiovascular disease, so in this case 10 years of OFS is something to consider, maybe OFS for 5 years and continuing tamoxifen could be a good strategy, bisphosphonates as prevention of bone loss is another good recommendation. I agree with the importance of Brca status in this patient.


  • Olivera Ivanov

    What about radiotherapy of the thoracic wall?


  • Sep 27, 2020

    Pending Moderator approval.
    Delete

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