We have detected that you are using an Ad Blocker.
PracticeUpdate is free to end users but we rely on advertising to fund our site. Please consider supporting PracticeUpdate by whitelisting us in your ad blocker.
We have sent a message to the email address you have provided, . If this email is not correct, please update your settings with your correct address.
The email address you provided during registration, , does not appear to be valid. Please update your settings with a valid address before to continue using PracticeUpdate.
Please provide your AHPRA Number to ensure that you are given the correct level of access to our site.

Expert Opinion / Cases · November 27, 2019

Multifocal Lobular in Young Pre-menopausal Woman—Treatment Opinions?

Trish O’Brien


Discuss This item Follow

No comments yet, be the first to start the discussion!

  • Saiji Nageshwaran

    Could also give 4x 2 weekly dose dense Paclitaxel instead of weekly. Also consider BRCA and risk reduction contralateral if not already done.

  • Isabel Pimentel

    BRCA status? I would consider her for a clinical trial with cdKi in the adjuvant setting.

  • Stefan Todorov

    Neoadjuvant cdk4/6 inhibitor plus aromataseinhibitor?

  • Carlos Calderon

    The ovarian ablation, premature menopause may be associated with long-term health effects, including cardiovascular disease, so in this case 10 years of OFS is something to consider, maybe OFS for 5 years and continuing tamoxifen could be a good strategy, bisphosphonates as prevention of bone loss is another good recommendation. I agree with the importance of Brca status in this patient.

  • Olivera Ivanov

    What about radiotherapy of the thoracic wall?

  • Jan 27, 2021

    Pending Moderator approval.

Further Reading