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In this report, the authors highlight a case in which a COVID-19 patient underwent lung transplantation.
There is limited literature about COVID-19 and lung transplantation. This case report adds to the literature on the subject and provides rationale for this management strategy for select patients with COVID-19 respiratory failure.
– Morgan Soffler, MD
This abstract is available on the publisher's site.
Most patients with COVID-19 have a mild or asymptomatic disease course; however, about 10% require admission to an intensive care unit (ICU) because of acute respiratory distress syndrome (ARDS).1, 2 Mortality rates of up to 60% have been reported for this subgroup.3, 4 Lung transplantation remains the ultimate treatment option for various chronic end-stage lung diseases. In addition, it can be considered as a salvage therapy for carefully selected patients who have severe treatment-refractory ARDS.5 However, wide uncertainty exists as to whether lung transplantation could have a place in the treatment of severe COVID-19 and, if so, what the optimal timing for such a treatment should be. Herein, we report the first case of lung transplantation for a patient with a persistently positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) real-time RT-PCR test result.
Lung Transplantation for COVID-19-Associated Acute Respiratory Distress Syndrome in a PCR-Positive Patient
Lancet Respir Med 2020 Aug 25;[EPub Ahead of Print], C Lang, P Jaksch, MAl Hoda, G Lang, T Staudinger, E Tschernko, B Zapletal, S Geleff, H Prosch, R Gawish, S Knapp, O Robak, F Thalhammer, A Indra, M Koestenberger, R Strassl, T Klikovits, K Ali, G Fischer, W Klepetko, K Hoetzenecker, P Schellongowski