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Ana Misir Krpan
I would recommend observation and close follow-up.
No adjuvant therapy, just periodical MRI control. I would suggest bimonthly MRI at least for the first year
Serial MRI surveillance every 2-3 months. I would also recommend NGS of the tumor specimen.
I agree with previous comments. At this time I would recommend close follow-up.
Glioneuronal tumors occur more commonly in children than in adults, are often lower grade, frequently associated with seizures, and a significant number are characterized by BRAFV600E dysregulation. The exact management following surgery remains ill-defined; a recent report from St. Jude's suggested that "high-risk" can be defined as diffuse astrocytic histology and/or midbrain/thalamic location" and speculated that post-operative radiotherapy might be beneficial in such a situation.
This patient does not have such high risk features and observation with surveillance is a very reasonable strategy.
Pending Moderator approval.
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