We have detected that you are using an Ad Blocker. PracticeUpdate is free to end users but we rely on advertising to fund our site. Please consider supporting PracticeUpdate by whitelisting us in your ad blocker.
We have sent a message to the email address you have provided, . If this email is not correct, please update your settings with your correct address.
The email address you provided during registration, , does not appear to be valid. Please update your settings with a valid address before to continue using PracticeUpdate.
No comments yet, be the first to start the discussion!
Ana Misir Krpan
I would recommend observation and close follow-up.
No adjuvant therapy, just periodical MRI control. I would suggest bimonthly MRI at least for the first year
Serial MRI surveillance every 2-3 months. I would also recommend NGS of the tumor specimen.
I agree with previous comments. At this time I would recommend close follow-up.
Glioneuronal tumors occur more commonly in children than in adults, are often lower grade, frequently associated with seizures, and a significant number are characterized by BRAFV600E dysregulation. The exact management following surgery remains ill-defined; a recent report from St. Jude's suggested that "high-risk" can be defined as diffuse astrocytic histology and/or midbrain/thalamic location" and speculated that post-operative radiotherapy might be beneficial in such a situation.
This patient does not have such high risk features and observation with surveillance is a very reasonable strategy.
The patient was observed and 2 month MRI brain was read as stable. However, repeat MRI 2 months later showed progression with a larger area of enhancement measuring 18 x 16 x 16 mm with increased rCBV, without significant surrounding edema. How would you proceed with management now?
Pending Moderator approval.
Are you sure you want to delete this comment? This can't be undone.