Gleason 9 Recurring as Gleason 10 s/p EBRT/HDR/HT
Patient presenting 5 years ago with a Gleason 9 (10/12 biopsies) and a PSA=9.7. Patient treated with EBRT/HDR/HT (6-month depot) with PSA dropping to less than 0.1 within one month of starting LHRH-agonist and before EBRT/HDR. Now with biological PSA recurrence and biopsy-proven disease of Gleason 10 (12/12 biopsies). Negative CT/bone scans. Too much disease for retreatment, prostatectomy, or cryotherapy. Without proven metastatic disease of castrate resistance, what choices are there outside of standard HT for a patient in good health without significant SE from previous therapies? Gland is approximately 17 cc with disease involving 90% by volume with current PSA=3.7 with 6-month doubling time.
Georg Potthast
Feb 16, 2018
Charles Maack
Feb 16, 2018
Richard Peksens
Feb 16, 2018
Charles Maack
Feb 19, 2018
Charles Maack
Feb 19, 2018
May 23, 2024
Pending Moderator approval.