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Published in Neurology

Journal Scan / Research · July 09, 2022

FAN1 Nuclease Activity Is Associated With the Slowing Down of CAG Expansion and Disease Onset in Huntington's Disease

Nature Neuroscience

 

Additional Info

Nature Neuroscience
Exome sequencing of individuals with Huntington's disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset
Nat Neurosci 2022 Apr 01;25(4)446-457, B McAllister, J Donaldson, CS Binda, S Powell, U Chughtai, G Edwards, J Stone, S Lobanov, L Elliston, LN Schuhmacher, E Rees, G Menzies, M Ciosi, A Maxwell, MJ Chao, EP Hong, D Lucente, V Wheeler, JM Lee, ME MacDonald, JD Long, EH Aylward, GB Landwehrmeyer, AE Rosser, , JS Paulsen, , NM Williams, JF Gusella, DG Monckton, ND Allen, P Holmans, L Jones, TH Massey

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

Further Reading