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Elderly patients are a very high–risk population in the COVID-19 pandemic and could derive tremendous benefit from the development of a vaccine. Elderly patients (age over 65) have historically been excluded in vaccine trials, and the goal of this study was to determine the ongoing inclusion of this population in current clinical SARS-CoV-2 vaccine trials. The analysis showed that up to 50% of clinical trials are actively excluding older adults for a variety of reasons.
Vaccine trials that proportionally include elderly adults are critical to the global success of a novel vaccine development. The scientific community needs to pay careful attention to the design of these clinical trials and demand adequate study in this most vulnerable population.
– Kolene E. Bailey, MD
This abstract is available on the publisher's site.