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Thank you for the case. In our practice in India, we prefer Pazopanib 400 mg od to start of initially and rise it to 800 mg if patient tolerates it. Sunitinib at 25 mg od two week on and 1 week off can also be given. We need to monitor LFT and TSH regularly
Sorafenib is better tolerated. Start with 200 mg bd .. Then escalate...
I agree with both pazopanib starting 400 mg die or sunitinib 25 mg die 2 week on/ 1 week off, following the patient with our multidisciplinary team of cardiologist.
Pending Moderator approval.
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