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Diet and Acne
abstract
This abstract is available on the publisher's site.
Access this abstract nowBACKGROUND
Dietary habits may play a non-negligible role in the development, duration, and severity of acne, as shown in past critical review articles on such association.
METHODS
The aim of this systematic review is to supplement data available on scientific literature spanning the last 10 years by inserting the keywords "acne" or "acne vulgaris" and "diet", "nutrition", "food", "chocolate", "dairy", "whey protein", "fatty acid", or "drink" in the timeframe "January 2009-April 2020" within the PubMed database.
RESULTS
Fifty-three reviewed articles met eligibility criteria. They included 11 interventional clinical trials (seven randomized controlled trials and four uncontrolled open label studies) and 42 observational studies (17 case-control and 22 cross-sectional studies, and three descriptive studies).
CONCLUSIONS
This review reinforces the notion of a rapidly growing exponential trend of interest in this subject by the scientific community. Acne-promoting factors include high GI/GL food, dairy products, fat food, and chocolate, whereas acne-protective factors include fatty acids, fruit, and vegetable intake. The role played by specific dietary components pertaining to different foods, as done for milk (full-fat/whole, reduced-fat, low-fat/skim milk), dairy products (milk cream, ice cream, yogurt, cheese, etc.), or chocolate (cocoa, dark/milk chocolate), remains an unsolved issue and objective of future research.
Additional Info
Disclosure statements are available on the authors' profiles:
Diet and Acne: Review of the Evidence From 2009 to 2020
Int. J. Dermatol 2021 Jan 18;[EPub Ahead of Print], F Dall'Oglio, MR Nasca, F Fiorentini, G MicaliFrom MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
The Acne Diet
The number of published research papers on nutrition and acne has been greater in the last 10 years than the previous 50. This systematic review summarizes the findings.
In general, what is good for the heart is also good for the skin, except for chocolate. The flavonoids in dark chocolate improve the endothelial lining and lower blood pressure for heart health, but chocolate may worsen acne. To see if it was the sugar or the chocolate, one study supplemented groups with chocolate or jelly beans. Despite similar amounts of sugar, the chocolate group had more acne lesions. Chocolate also remained a trigger for acne when dark chocolate was studied without added milk or sugar.
Diet influences hormones that are known to worsen acne. Eating a high glycemic diet triggers excess insulin, which causes weight gain and inflammation. The sugar load in fruit juices, soda, processed foods, and products made from white flour have a similar effect. Dairy is rich in estrogens, androgens, IGF-1, and bovine growth hormone. Both whole and skim milk contain acne-causing hormones, and, lastly, saturated fat from non-dairy sources also poses an inflammatory risk.
A Summary of the Acne Diet
Foods to Avoid in Descending Effect
Foods to Eat to Avoid Acne
Coming from someone who has designed and published a study (which was cited in this review) about chocolate consumption and acne, diet studies are perhaps some of the most difficult investigations in medicine. Nutritional research relies heavily on dietary recall, which is fraught with limitations, bias, and confounding variables as people tend to underreport “bad” foods and overreport “good” foods, while not paying close enough attention to ingredients and portions. Some critics of diet-based studies even go as far to claim that they do not follow the scientific method and should be regarded as pseudoscience. Despite these shortcomings, dietary advice that drives government policy comes from these kind of studies. Luckily, over the past decade, there has been a newfound renaissance of dietary research in the dermatology literature.
In this systematic review between January 2009 and April 2020, the authors evaluated 42 observational studies and 11 interventional clinical trials and found multiple dietary factors associated with acne. Specifically, the review found that acne-promoting factors include high GI/GL food, dairy products, fatty food, and chocolate, whereas acne-protective factors include fatty acids as well as fruit and vegetable intake.
High GI/GL foods lead to hyperglycemia and hyperinsulinemia, which induce elevated levels of IGF-1, thereby promoting keratinocyte hyperproliferation and increased androgen levels, which lead to hyperseborrhea and acne. Interestingly, the authors found that the advantages of low GI/GL diets are largely negated without concomitant weight loss. Dairy products (especially whole milk), generally need to be consumed at least 3 times weekly to exert a detrimental effect. Although milk has a low GI, its hormonal components paradoxically increase glucose and insulin, leading to the same downstream effects of increased IGF-1. In terms of fatty food, at least a daily intake of fried, spicy, oily, and fast food and saturated fatty acids and trans fatty acids were needed to elicit an acne-promoting effect. Chocolate, regardless of whether it was milk chocolate or 100% cocoa, was implicated as an aggravating and exacerbating factor for acne. Conversely, the review found that frequent (more than 3 days/week) fruit (green bananas, watermelon) and vegetables (yellow, green leaf, cruciferous, green peas) showed a protective role for acne, which was attributed to their anti-inflammatory and antioxidant properties. Furthermore, the Mediterranean diet (rich in fruits and vegetables) compared with the typical Western diet is considered by the authors to be a “food model” for acne patients.
In the real world, diet and dermatology-related questions are common, almost daily, discussions that I have with patients in my clinic. Many of my patients have expressed frustration that previous providers did not take their claims seriously. Instead of quickly dismissing my patients concerns due to lack of convincing well-designed studies, I listen. These types of discussions tend to go better when shifting the doctor–patient relationship from paternalistic to collaborative. To help better validate my patients, I recommend that they keep a food diary, which can help identify dietary patterns around skin condition flares, and, more times than not, we find something.