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The authors review the available literature regarding the cardiovascular considerations of the current COVID-19 pandemic. Patients with preexisting cardiovascular disease (CVD) plus COVID-19 have an increased risk of severe illness and death compared with patients without CVD. In addition, COVID-19 appears to have multiple cardiovascular complications, such as acute myocardial injury, myocarditis, arrhythmias, and venous thromboembolism. Current therapies under review may impact the cardiovascular system. Healthcare workers are especially vulnerable to infection or to becoming host or vectors of virus transmission.
The cardiovascular community has a key role to play in the management of patients affected by COVID-19 as well as in the continued management of patients with established CVD who are at high-risk for severe infection.
This abstract is available on the publisher's site.
The coronavirus disease-2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 that has significant implications for the cardiovascular care of patients. First, those with COVID-19 and preexisting cardiovascular disease (CVD) have an increased risk of severe disease and death. Second, infection has been associated with multiple direct and indirect cardiovascular complications including acute myocardial injury, myocarditis, arrhythmias and venous thromboembolism. Third, therapies under investigation for COVID-19 may have cardiovascular side effects. Fourth, the response to COVID-19 can compromise the rapid triage of non-COVID-19 patients with cardiovascular conditions. Finally, the provision of cardiovascular care may place health care workers in a position of vulnerability as they become host or vectors of virus transmission. We hereby review the peer-reviewed and preprint literature pertaining to cardiovascular considerations related to COVID-19 and highlight gaps in knowledge that require further study pertinent to patients, health care workers, and health systems.