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Expert Opinion / Cases · October 30, 2020

Chemotherapy or Only Endocrine Therapy?

Written by
Ana C. Sandoval Leon MD


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  • mehrdad payadeh

    Chemotherapy due to high Ki67

  • Bogdan Cristian Dinu

    Chemo based by PgR level , LVI and Ki67

  • luis betancourt

    Chemotherapy. Radiotherapy?

  • zjc0305@live.cn zjc0305@live.cn

    Chemotherapy should be recommended. The benefit and potential hazard should be fully discussed with the patient, based on her high Ki67, LVI, relatively young age. Besides, information related to tumor grade and menopausal status should be provided for detailed discussion.

  • giovanni marini

    chemioterapia seguita da ormonoterapia (Google translate: chemotherapy followed by hormonal therapy)

  • Kendra Dean

    Chemo due to age, male and Ki67

  • neil lins

    QT + HT

  • Raphael Catane

    Why performing Oncotype, if you don't follow its recommendation.

  • Serkan Akin

    Ki67 of final path report should be considered. Oncotype score could also be reliable in males. However I think the most necessary issue should be to check BRCA and other germline mutations in this guy. Eventually I want to start him tamoxifen for 5 years with close follow-up


    oncotype in male breast cancer is rarely used, but it serves to avoid over-treating patients, experience is limited, but would only indicate hormonal therapy based on the oncotype score

  • Sewa Legha

    Male Breast Cancer is highly sensitive to Hormonal therapy. So it is generally the preferred first option of treatment. In addition to endocrine therapy, a case can be made to adding chemotherapy to high risk patients(such as those with Lymph node metastases. Since this patient has node negative disease, I would not recommend any chemotherapy. Instead use endocrine therapy such as Tamoxifen for a duration of 5 years. Sewa S. Legha, MD

  • Del Barco Sonia

    First, if you do oncotype .. you follow it or not? Second, in case of woman i choose chemo because age and therefore in this case, the same

  • Ludwing Bacon Fonseca

    If I send a Genomic profile.... I should follow the recommendation.... so my personal opinion with all information is : Tamoxifen x 5a

  • Jul 26, 2021

    Pending Moderator approval.

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