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Published in Cardiology

Expert Opinion / Commentary · June 15, 2015

Brugada Syndrome and the Questionable Prognostic Value of Programmed Electrical Stimulation

Written by
Silvia G Priori MD


Additional Info

  1. Priori SG, Wilde AA, Horie M, et al. HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes: document endorsed by HRS, EHRA, and APHRS ACCF, AHA, PACES, and AEPC. Heart Rhythm. 2013;10(12):1932-63.
  2. Brugada J, Brugada R, Antzelevitch C, Towbin J, Nademanee K, Brugada P. Long-term follow-up of individuals with the electrocardiographic pattern of right bundle-branch block and ST-segment elevation in precordial leads V1 to V3. Circulation. 2002;105(1):73-78.
  3. Priori SG, Napolitano C, Gasparini M, et al. Clinical and genetic heterogeneity of right bundle branch block and ST-segment elevation syndrome: A prospective evaluation of 52 families. Circulation. 2000;102(20):2509-2515.
  4. Priori SG, Napolitano C, Gasparini M, et al. Natural history of Brugada syndrome: insights for risk stratification and management. Circulation. 2002;105(11):1342-1347.
  5. Gasparini M, Priori SG, Mantica M, et al. Programmed electrical stimulation in Brugada syndrome: how reproducible are the results? J Cardiovasc Electrophysiol. 2002;13(9):880-887.

  6. Sieira J, Conte G, Ciconte G, et al. Prognostic value of programmed electrical stimulation in brugada syndrome: 20 years experience [published online April 22, 2015]. Circ Arrhythm Electrophysiol. doi: 10.1161/CIRCEP.114.002647.
  7. Brugada J, Brugada R, Brugada P. Determinants of sudden cardiac death in individuals with the electrocardiographic pattern of Brugada syndrome and no previous cardiac arrest. Circulation. 2003;108(25):3092-3068.
  8. Priori SG, Gasparini M, Napolitano C, et al. Risk stratification in Brugada syndrome: results of the PRELUDE (PRogrammed ELectrical stimUlation preDictive valuE) registry. J Am Coll Cardiol. 2012;59(1):37-45.
  9. Probst V, Veltmann C, Eckardt L, et al. Long-term prognosis of patients diagnosed with Brugada syndrome: Results from the FINGER Brugada Syndrome Registry. Circulation. 2010;121(5):635-643.

Further Reading