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hormonal tx and re-evaluation in 2-3 months
hsien tang yeh
under sona-guided FNA of axillary LN to prove metastasis indicated, as after neoadjuvant treatment, the axillary surgery option depends on pre-treatment and post-treatment condition,Ki 67 count also a predict factor as chemo or hormone be the first treatment.
Is there the possibility to enroll the patient in a neoadjuvant clinical trial with hormonal therapy and cdk4/6 inhibitors?
LuA; neo endocrine tx
The node; should be bx
This is a very high risk situation with bilateral Breast Cancer, with locally advanced disease on one side . Therefore she will need all modalities of treatment including chemo, endocrine therapy, surgery and most likey XRT at the end of systemic therapy.. As she will need both hormonal therapy and chemotherapy, these will need to be used sequentially. Since the neoadjuvant endocrine therapy experience is much more limited in comparison to neoadjuvant chemotherapy, I would recommend starting with Neoadjuvant chemo using a combination of 2 cytotoxic agents followed by local therapy (?bilateral mastectomy) and at the end using endocrine therapy as adjuvant therapy.
In rt axilla need for sentinel L N biopsy to confirm diagnosis
Pending Moderator approval.
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