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story of the week
Published in Primary Care

Journal Scan / Research · September 14, 2022

Amitriptyline Supplemented With Pregabalin vs Pregabalin Supplemented With Amitriptyline vs Duloxetine Supplemented With Pregabalin for the Treatment of Diabetic Peripheral Neuropathic Pain

The Lancet


Additional Info

Disclosure statements are available on the authors' profiles:

The Lancet
Comparison of amitriptyline supplemented with pregabalin, pregabalin supplemented with amitriptyline, and duloxetine supplemented with pregabalin for the treatment of diabetic peripheral neuropathic pain (OPTION-DM): a multicentre, double-blind, randomised crossover trial
Lancet 2022 Aug 27;400(10353)680-690, S Tesfaye, G Sloan, J Petrie, D White, M Bradburn, S Julious, S Rajbhandari, S Sharma, G Rayman, R Gouni, U Alam, C Cooper, A Loban, K Sutherland, R Glover, S Waterhouse, E Turton, M Horspool, R Gandhi, D Maguire, EB Jude, SH Ahmed, P Vas, C Hariman, C McDougall, M Devers, V Tsatlidis, M Johnson, ASC Rice, D Bouhassira, DL Bennett, D Selvarajah

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

Further Reading