Download from app store
We have detected that you are using an Ad Blocker.
PracticeUpdate is free to end users but we rely on advertising to fund our site. Please consider supporting PracticeUpdate by whitelisting us in your ad blocker.
We have sent a message to the email address you have provided, . If this email is not correct, please update your settings with your correct address.
The email address you provided during registration, , does not appear to be valid. Please update your settings with a valid address before to continue using PracticeUpdate.
Please provide your AHPRA Number to ensure that you are given the correct level of access to our site.

Journal Scan / Research · November 02, 2022

A Selective and Orally Bioavailable VHL-Recruiting PROTAC Achieves SMARCA2 Degradation

Nature Communications


Additional Info

Nature Communications
A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
Nat Commun 2022 Oct 10;13(1)5969, C Kofink, N Trainor, B Mair, S Wöhrle, M Wurm, N Mischerikow, MJ Roy, G Bader, P Greb, G Garavel, E Diers, R McLennan, C Whitworth, V Vetma, K Rumpel, M Scharnweber, JE Fuchs, T Gerstberger, Y Cui, G Gremel, P Chetta, S Hopf, N Budano, J Rinnenthal, G Gmaschitz, M Mayer, M Koegl, A Ciulli, H Weinstabl, W Farnaby

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

Further Reading