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Expert Opinion / Cases · November 07, 2022

75yo Female With Suspected Metastatic TNBC and Suspicious Bone Metastases on Imaging but Multiple Negative Biopsies

Written by
Jing Xi MD, MPH


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  • Kristine Blake

    Nov 08, 2022

    Did they do biopsies CT guided?  I have lobular, and my cancer was missed for six years because they thought it was multiple myeloma. It was breast cancer, but they failed to pursue further testing. They did a bone marrow biopsy that was not CT guided and didn’t pick tissue with cancer. In 2020, I had a CT guided bone biopsy, and it was found. The cancer spread to my stomach because of the missed diagnosis. 

  • Laura Nadeau

    Nov 11, 2022

    Did you attempt liquid biopsy? 

  • Bogdan Cristian Dinu

    Nov 12, 2022

    I think is not a bone metastatic disease , probably the long period of recover after two chemoterapy seances,was in liason of avascular sclerosis. Check for N telopeptide X,  oseose ALP , bone scintigraphy.

  • thawatchai dudsadeeprasert

    Nov 20, 2022

    Is it Paget disease of bone?

  • mehrdad payadeh

    Dec 18, 2022

    Due to severe 
    Severe neutropenia can prepare for tightly infection and chronic osteomyelitis 

  • May 30, 2024

    Pending Moderator approval.

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