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Brain Cancer
Center of Excellence
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srinivas rao
Aug 06, 2021
Mri brain with contrast and perfusion
Amir Azadi
Aug 06, 2021
NGS of the tumor?
Saurabh Didwania
Aug 06, 2021
Ok We will go for MRI within 7 days .
Sir is it 100 percent sure that recurrence will occur or there is any chance that recurrence will not occur again after GTR and radiation .
Minesh Mehta
Aug 27, 2021
The role of temozolomide in unmethylated GBM remains a controversial issue; however, this patient has already had 4 cycles, and I would complete an additional 2 cycles to complete 6. Going by level 1 data, one could still potentially consider adding TTField therapy, as there is a randomized trial demonstrating survival advantage, irrespective of methylation status. NGS has a small probability of yielding an actionable mutation, but if possible, could be considered. Recurrence is most likely at some point down the line, although all of us have the very few exceptional patients that have become long-term survivors, and therefore, in someone who has had a gross total resection, I would never take hope away.
Saurabh Didwania
Nov 12, 2021
Dear All
Thanks for the suggestions .Now the patient has completed 7 cycles of temozolomide .
Physically and mentally fit after 11 months of surgery
Any other suggestions.
Saurabh Didwania
Mar 21, 2022
11 cycles of temozolomide completed no physical imbalance in memory or in walking eating and sleeping .dr is saying to go for mri after 12 cycles .pls suggest
srinivas rao
Mar 22, 2022
I agree with your doctor
Mayer Gorbaty
Mar 22, 2022
I have a question for the group. What is the optimal # of cycles for adjuvant temozolomde? Is it 6? 12? indefinitely until progression?
srinivas rao
Mar 22, 2022
This question is infact quite interesting.There is no definite answer for this.Usually i give upto 12 cycles if the patient is tolerating well symptomatically,lab wise n imaging wise.But if you see the literature there are few anecdotal papers where TMZ was given for 101 cycles.So it is your Oncologist who has to decide
Saurabh Didwania
Apr 15, 2022
12 cycles of temozolomide completed no physical imbalance in memory or in walking eating and sleeping .when to go for MRI or to give any other medication .pls suggest
Saurabh Didwania
Apr 27, 2022
Any other treatment suggestions by any one .What treatment we can continue as 12 cycles of temozolomide completed so that recurrence can be controlled
Saurabh Didwania
Jul 03, 2022
17 months completed without any symptoms .No MRI done till now after surgery .
Is MRI suggested ?
No complains no symptoms .
Walking +speech + memory all good .
Apr 19, 2024
Pending Moderator approval.
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srinivas rao
Aug 06, 2021
Amir Azadi
Aug 06, 2021
Saurabh Didwania
Aug 06, 2021
Minesh Mehta
Aug 27, 2021
Saurabh Didwania
Nov 12, 2021
Saurabh Didwania
Mar 21, 2022
srinivas rao
Mar 22, 2022
Mayer Gorbaty
Mar 22, 2022
srinivas rao
Mar 22, 2022
Saurabh Didwania
Apr 15, 2022
Saurabh Didwania
Apr 27, 2022
Saurabh Didwania
Jul 03, 2022
Apr 19, 2024
Pending Moderator approval.