We have detected that you are using an Ad Blocker.
PracticeUpdate is free to end users but we rely on advertising to fund our site. Please consider supporting PracticeUpdate by whitelisting us in your ad blocker.
We have sent a message to the email address you have provided, . If this email is not correct, please update your settings with your correct address.
The email address you provided during registration, , does not appear to be valid. Please update your settings with a valid address before to continue using PracticeUpdate.
Please provide your AHPRA Number to ensure that you are given the correct level of access to our site.
featured

Expert Opinion / Cases · June 04, 2021

54 y/o Male With a History of Diabetes Mellitus, Presumed to be LADA (Positive GAD-65) Presents for a Second Opinion

Written by
Jacqueline A. Seiglie MD, MSc

 

Discuss This item Follow

No comments yet, be the first to start the discussion!

  • Chandrakant Madgaonkar

    In this case, 54y/0, LADA with positive GAD antibodies, and strong family H/O DM , and HBA1c 8%, low BMI, a combination of metformin with DPP–4 inhibitors, or SGLT2 inhibitors, with Vitamin D3 can be considered (in place of insulin); further consider to rule out other auto-immune disorders such as thyroid dysfunction ... etc. Thank you.


  • Javier Morales

    I have a similar patient with a similar story. Again, intolerance to injectable GLP one therapy and SGL T2 inhibitor therapy resulted in significant and severe dyslipidemia. Currently, and for physiologic replacement and believe it or not, seems to have better glycemic control on Janumet than when on a GLP1 , Possibly due to glucagon suppression. The curious thing was the better glycemic control while on DPP4 Which makes me question his adherence with GLP one. As a rule, I stay way from SUs


  • Jun 14, 2021

    Pending Moderator approval.
    Delete

Further Reading