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Published in Urology

Expert Opinion / Commentary · December 11, 2021

2021 Top Story in Urology: Taking Another Look at Clorpactin and Cyclosporine

Written by
Philip M. Hanno MD, MPH

 

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Additional Info

  1. Mertz JH, Nourse MH, WISHARD WN,. Use of clorpactin WCS 90 for relief of symptoms due to interstitial cystitis. Trans Am Assoc Genitourin Surg. 1956;48:86-89.

  2. Wishard W, Nourse MH, Mertz JH. Use of clorpactin WCS 90 for relief of symptoms due to interstitial cystitis. J Urol. 1957;77(3):420-423.

  3. Murnaghan GF, Saalfeld J, Farnsworth RH. Interstitial cystitis – treatment with chlorpactin WCS 90. Br J Urol. 1970, Dec;42(6):744.

  4. Messing EM, Stamey TA. Interstitial cystitis: Early diagnosis, pathology, and treatment. Urology. 1978;12(4):381-392.

  5. Cvach K, Rosamilia A, Dwyer P, et al. Efficacy of clorpactin in refractory bladder pain syndrome/interstitial cystitis: A randomized controlled trial. Int Urogynecol J. 2021;32(5):1177-1183.
  6. Messing EM, Freiha FS. Complication of clorpactin WCS90 therapy for interstitial cystitis. Urology. 1979;13(4):389-392.

  7. Forsell T, Ruutu M, Isoniemi H, et al. Cyclosporine in severe interstitial cystitis. J Urol. 1996;155(5):1591-1593.

  8. Sairanen J, Forsell T, Ruutu M. Long-term outcome of patients with interstitial cystitis treated with low dose cyclosporine A. J Urol. 2004;171(6 Pt 1):2138-2141.
  9. Crescenze IM, Tucky B, Li J, et al. Efficacy, side effects, and monitoring of oral cyclosporine in interstitial cystitis/bladder pain syndrome. Urology. 2017;107:49-54.
  10. Vollstedt A, Tennyson L, Turner K, et al. Evidence for early cyclosporine treatment for Hunner lesion interstitial cystitis. Female Pelvic Med Reconstr Surg. 2021, Sep 30. doi: 10.1097/SPV.0000000000001108. Online ahead of print.
  11. Di XP, Luo DY, Jin X, et al. Efficacy and safety comparison of pharmacotherapies for interstitial cystitis and bladder pain syndrome: A systematic review and bayesian network meta-analysis. Int Urogynecol J. 2021;32(5):1129-1141.
  12. Khojah MI, Badeghiesh AM, Ismail S, et al. Interstitial cystitis/bladder pain syndrome's correlations with pregnancy and neonatal outcomes: A study of a population database. J Urol. 2021;206(4):978-985.
  13. Nickel JC, Doiron RC. Hunner lesion interstitial cystitis: The bad, the good, and the unknown. Eur Urol. 2020; 78(3):e122-e124.
  14. Hanno P, Fall M, Meijlink J, Nordling J. Towards a new paradigm in bladder pain syndrome and interstitial cystitis. BJU Int. 2020;126(5):549-550.
  15. Plair A, Evans RJ, Langefeld CD, et al. Anesthetic bladder capacity is a clinical biomarker for interstitial cystitis/bladder pain syndrome subtypes. Urology. 2021, Jul 22. doi: 10.1016/j.urology.2021.07.009. Online ahead of print.
  16. Lai HH, Newcomb C, Harte S, et al. Comparison of deep phenotyping features of UCPPS with and without Hunner lesion: A MAPP-II research network study. Neurourol Urodyn. 2021;40(3):810-818.

Disclosure statements are available on the authors' profiles:

Philip Hanno MD, MPH

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