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Published in Neurology

Expert Opinion / Commentary · December 07, 2020

2020 Top Stories in Neurology: When Does Parkinson Disease Begin and What is Parkinson Disease Anyway?

Written by
Mark Hallett MD


Additional Info

  1. Barone DA, Henchcliffe C. Rapid eye movement sleep behavior disorder and the link to alpha-synucleinopathies. Clin Neurophysiol. 2018;129(8):1551-1564.
  2. Postuma RB, Iranzo A, Hu M, et al. Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study. Brain. 2019;142:744-759.
  3. Schaeffer E, Postuma RB, Berg D. Prodromal PD: a new nosological entity. Prog Brain Res. 2020;252:331-356.
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  6. Videnovic A. MScREM sleep atonia loss distinguishes synucleinopathy in older adults with cognitive impairment. PracticeUpdate website. Accessed November 13, 2020.
  7. McCarter SJ, Sandness DJ, McCarter AR, et al. REM sleep muscle activity in idiopathic REM sleep behavior disorder predicts phenoconversion. Neurology. 2019;93(12):e1171-e1179.
  8. Dijkstra F, Van den Bossche K, de Bruyn B, et al. REM sleep without atonia and the relation with Lewy body disease. Parkinsonism Relat Disord. 2019;67:90-98.
  9. Dede HO, Benbir Senel G, Karadeniz D. Rapid eye movement sleep without atonia constitutes increased risk for neurodegenerative disorders. Acta Neurol Scand. 2019;140(6):399-404.
  10. Figorilli M, Marques AR, Vidal T, et al. Does REM sleep behavior disorder change in the progression of Parkinson's disease? Sleep Med. 2020;68:190-198.

Disclosure statements are available on the authors' profiles:

Further Reading