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Steven Grinspoon MD

Steven K. Grinspoon MD

Professor of Medicine, Harvard Medical School, Boston, Massachusetts

Dr. Steven Grinspoon is a Professor of Medicine, Harvard Medical School, Chief of the MGH Metabolism Unit, and Director of the Nutrition Obesity Research Center at Harvard. He has had a long-standing interest in the metabolic and immune complications of HIV disease.

He chaired the American Heart Association State of the Science Conference on Cardiovascular Disease in HIV-infected patients. His work has suggested significant cardiovascular disease in people with HIV (PWH) and highlighted the relative contributions of traditional risk factors, including diabetes and excess visceral fat accumulation, and of nontraditional risk factors, including inflammation and immune activation, using novel PET and CT techniques linking arterial inflammation to high risk vulnerable plaque. In this regard, he is a co-leader of the 7700 participant, global NIH-funded REPRIEVE study to prevent cardiovascular disease in HIV.

In addition, he has shown efficacy of strategies to improve ectopic adipose tissue, leading the development of an FDA approved strategy for visceral fat reduction. For his work, Dr. Grinspoon was awarded the 2016 Aurbach Laureate award in translational research from the Endocrine Society.

Dr. Grinspoon is a member of the American Society of Clinical Investigation and the Association of American Physicians, honoring his achievements.


Dr. Grinspoon discloses the following:
  • NIH
  • Gilead
  • Kowa
  • Viiv
  • Theratechnologies
  • Marathon Asset Management

Recent Contributions to PracticeUpdate:

  1. Pitavastatin for Preventing CVD in Patients With HIV Infection