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Senthil Selvaraj MD, MS, MA

Senthil Selvaraj MD, MS, MA

Assistant Professor of Medicine, Division of Cardiology, Duke University School of Medicine and Duke Molecular Physiology Institute, Durham, North Carolina

Senthil Selvaraj, MD, MS, MA, is an Assistant Professor of Medicine in the Division of Cardiology at Duke University Medical Center and faculty member in the Duke Molecular Physiology Institute. Dr. Selvaraj completed undergraduate and medical school training at Northwestern University through the Honors Program in Medical Education. He received a Masters degree in the medical humanities and bioethics. At the Brigham and Women’s Hospital, he completed internal medicine residency, chief residency, and a preventive cardiology fellowship. During his time at the University of Pennsylvania, he completed general cardiology with advanced training in multimodality imaging and heart failure and transplant cardiology. He also received a Master’s degree in translational research at the University of Pennsylvania.

Dr. Selvaraj’s translational research explores the therapeutic relevance of cardiovascular metabolism to patients with heart failure. Through early phase work, his research employs deep phenotyping to decipher metabolic mechanisms that may be leveraged for cardiovascular benefit. These studies characterize dynamic changes in exercise physiology, biomarker profiles integrating multi-omic platforms, echocardiography, arterial stiffness, metabolic molecular imaging techniques, and several other modalities. More recently, this line of inquiry has explored the potential benefits of endogenous and exogenous ketogenic therapies among patients with heart failure. Dr. Selvaraj’s work is currently or recently funded by the National Institutes of Health, American Heart Association, Doris Duke Charitable Foundation, Mandel Foundation, Heart Center Leadership Council, Institute for Translational Medicine and Therapeutics, and American Society for Nuclear Cardiology.


Dr. Selvaraj receives research support from the National Heart, Lung, and Blood Institute (K23HL161348), Doris Duke Charitable Foundation (#2020061), American Heart Association (#935275), the Mandel Foundation, Duke Heart Center Leadership Council, and the Institute for Translational Medicine and Therapeutics.