Paul Nghiem MD, PhDProfessor & Head, George F. Odland Endowed Chair, Division of Dermatology, Professor, Adjunct, of Immunology, Laboratory Medicine & Pathology and Oral Health Sciences, University of Washington; Affiliate Investigator & Clinical Director of Skin Oncology, Fred Hutchinson Cancer Center, Seattle, Washington
Dr. Paul Nghiem (pronounced KNEE-em) is the George F. Odland Endowed Chair and Head of the Division of Dermatology at the University of Washington in Seattle. He sees patients at the Fred Hutchinson Cancer Center.
He grew up in Olympia, Washington, attended Harvard College and then obtained MD and PhD degrees at Stanford University where he studied Cancer Biology and Immunology.
He did his medicine internship at Brigham and Women's Hospital in Boston followed by Dermatology residency at Massachusetts General Hospital. He worked on UV-DNA damage responses as a Howard Hughes Post-Doctoral Fellow with Stuart Schreiber in the Department of Chemistry and Chemical Biology at Harvard University.
In 2003, he started his own lab at the Cutaneous Biology Research Center at Massachusetts General Hospital.
In 2006, together with their two young boys, he and his wife moved 'home' to Seattle. He has published over 170 papers that in aggregate have been cited over 18,000 times.
In 1996, as a dermatology resident, Dr. Nghiem saw a man with a firm lesion on the lip that turned out to be his first case of Merkel cell carcinoma. He was later encouraged by his professors to write a book chapter on this rare disease. Surprisingly, MCC patients began coming regularly to his clinic for help with this complicated cancer.
Today, he leads a multi-disciplinary team focused on improving management of MCC. Studies led by his team resulted in the first two FDA-approved therapies for MCC, as well as a blood test that is now routinely used clinically to detect recurrent MCC earlier and more reliably than scans.
He has several grants from the NIH, including a Program Project Grant that brings together diverse scientists to study the immune response to MCC and the Merkel polyomavirus that typically causes this cancer.
Given his long-term interest in cancer biology and immunology, Dr. Nghiem feels very fortunate to study a disease in which cancer immunology has improved the lives of patients, who in turn are passionately engaged in improving the outcomes for this unusual cancer.
Research support for his institution from Incyte
Research support for his institution from Bristol Myers Squibb
Consulting fees for Almirall
Recent Contributions to PracticeUpdate:
- Risk of Multiple Primary Cancers in Patients With Merkel Cell Carcinoma
- Efficacy and Safety of Adjuvant Nivolumab in Patients With Completely Resected Merkel Cell Carcinoma
- Impact of Clinical Excision Margins and Mohs Micrographic Surgery on Recurrence and Survival of Patients With MCC
- Mohs Surgery Monotherapy for Early-Stage Merkel Cell Carcinoma
- Association Between Treatment Center Experience and Survival After Diagnosis of Stage I–III Merkel Cell Carcinoma