We have detected that you are using an Ad Blocker.
PracticeUpdate is free to end users but we rely on advertising to fund our site. Please consider supporting PracticeUpdate by whitelisting us in your ad blocker.
We have sent a message to the email address you have provided, . If this email is not correct, please update your settings with your correct address.
The email address you provided during registration, , does not appear to be valid. Please update your settings with a valid address before to continue using PracticeUpdate.
Please provide your AHPRA Number to ensure that you are given the correct level of access to our site.
James Lewis

James D. Lewis MD, MSCE

Professor of Medicine and Epidemiology; Director of Clinical Research, Division of Gastroenterology and Hepatology; Interim Chief of Gastroenterology and Hepatology, Penn Presbyterian Medical Center and the Center for Digestive and Liver Health University City, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

James Lewis, MD, MSCE, is Professor of Medicine and Epidemiology, Senior Scholar in the Center for Clinical Epidemiology and Biostatistics, LDI Senior Fellow and Associate Director of the Inflammatory Bowel Disease program at the University of Pennsylvania’s Perelman School of Medicine in Philadelphia, Pennsylvania. Dr. Lewis also directs the Gastroenterology and Hepatology Clinical Research Program at the University of Pennsylvania.

Dr. Lewis has been actively involved in clinical research related to inflammatory bowel diseases, medication safety, and optimizing medical therapies for more than 20 years. More recently, he has focused on the impact of diet on the gut microbiome and the course of inflammatory bowel disease. His work has been funded by the NIH, AHRQ, PCORI, and numerous foundations and corporate sponsors. He is currently leading a nationwide clinical trial comparing the specific carbohydrate diet to a Mediterranean style diet for Crohn’s disease. He is also working on methods to more efficiently document and share data collected in routine care for research while improving patient-physician engagement. Dr. Lewis previously served as the Chair of the National Scientific Advisory Committee and a member of the National Board of the Crohn’s & Colitis Foundation. He is currently the lead scientist for the Foundation’s IBD Plexus Research. He is an elected member of the American Society for Clinical Investigation and the Association of American Physicians.

Dr. Lewis is also committed to training the next generation of physician scientists focused on just intestinal diseases. He is the principle investigator of two training grants from NIDDK. In 2018, he received the American Gastroenterological Association’s Distinguished Educator Award. To date, he has served as either the primary or secondary mentor for more than 25 gastroenterology or oncology fellows of whom more than 70% have remained in academic careers and many have gone on to obtain career development and independent research.


Dr. Lewis has received research funding, consulting honorarium, and honorarium for participation in medical education activities from Nestle Health Science.