Emmanuel Messas MD, PhD, FESC

Pr. Emmanuel Messas is MD, PhD, and Fellow of European Society of Cardiology, Head of Cardiovascular (CV) prevention and Vascular Medicine department at Hopital Européen Georges Pompidou, Université of Paris Cité and Inserm UMR 970, Paris, France. His main field of research is innovation in CV ultrasound imaging and therapy.

He was research fellow in 1999-2001 in Cardiac ultrasound lab of Massachusetts General Hospital, Harvard Medical School under the supervision of Robert A. Levine world known cardiologist on ultrasound and valve. Since his fellowship, all his research was to use ultrasound imaging innovative technique to better understand heart valve disease in order to cure them by non invasive ultrasound therapy. He developed a new technique called " chordal cutting" for ischemic mitral regurgitation based on its mechanism called "apical tenting" describe by cardiac ultrasound.

Since 15 years, he forged as strong collaboration with world leader in Ultrasound Physics from Ecole Superior of Physics and Chemistry of Paris (ESPCI),Paris,France initially with Mathias Fink in Langevin institute and today with Mathieu Pernot and Mickael Tanter from INSERM team Physics for Medicine. Using UItrafastecho imaging, Shear wave imaging, and Ultrafast Doppler they developed new research on arterial plus wave velocity, arterial wall stiffness, atherosclerosis plaque biomechanics evaluation. Their collaboration continues on the cardiac function evaluation using elastography and shear wave imaging for myocardial stiffness evaluation in preserved ejection heart failure patients.

Finally, since 8 years they fund a start up company called CardiawaveÒ which developed a breakthrough disruptive technology on non invasive ultrasound therapy creating shockwave on the embedded calcification of the aortic valve of patient with severe symptomatic aortic valve stenosis.

Pr. Messas is the PI of the international first in human study on this application. Already some promising result has been presented in multiple international cardiology meeting as European Society of Cardiology scientific meeting and American Heart Association meeting. The first 10 patients with 30 days follow up were published in Circulation in 2021 and more recently the 6 month follow up was published in The Lancet.

Today, he continues this fruitful collaboration on new approaches ultrasound bases for treatment and diagnosis of cardio vascular diseases.