David J. Young MD, PhD, FAAP

Dr. Young is a pediatric Hematologist and Oncologist who has pursued investigations of the clinical, translational, and basic science aspects of hematologic diseases, specifically bone marrow failure syndromes, both acquired and inherited, and myeloid malignancies. He has examined the molecular basis of therapy-related myeloid neoplasms, identified novel genetic changes in myeloid leukemia, and developed novel methods for targeting disease specific mutations such as FLT3. These works have led to multiple publications, abstracts at national society meetings, and even a patent. He has also led clinical trials examining the pharmacologic treatment of bone marrow failure, with a goal towards identifying effective, non-transplant therapies for these conditions. He graduated from the University of Notre Dame with a degree in Biochemistry and then from the University of Chicago Pritzker School of Medicine and Biological Sciences Division with a degree in medicine and a doctorate of Cancer Biology under the mentorship of Dr. Michelle M. Le Beau. After pediatric training at Hasbro Children’s Hospital and the Alpert Medical School of Brown University, completed a fellowship through the Johns Hopkins/National Institutes of Health combined Pediatric Hematology/Oncology program. He continued his post-doctoral research in the laboratory of Dr. Donald Small, examining the genetics, biology, and therapeutics of FLT3-mutated disease. In 2018, he returned to the NIH and joined the faculty of the National Heart, Blood, and Lung Institute as a Staff Clinician of the Translational Stem Cell Biology Branch, in the laboratory of Dr. Cynthia Dunbar where he continues his clinical and translational research.