David S. Goldstein MD, PhD

Dr. David S. Goldstein is an internationally recognized authority and clinical researcher in autonomic and catecholamine-related disorders. He graduated in 1970 from Yale College and completed an MD/PhD at Johns Hopkins in 1976. After internal medicine training at the University of Washington, in 1978 he came to the National Institutes of Health (NIH) as a Clinical Associate in the National Heart, Lung, and Blood Institute. He has been a tenured Senior Investigator in intramural NIH since 1984. In 1990 he transferred to the National Institute of Neurological Disorders and Stroke (NINDS), where he has been Chief of the Clinical Neurochemistry Section, the Clinical Neurocardiology Section, and the Autonomic Medicine Section. Dr. Goldstein has more than 600 publications (135 first-authored original research reports), with more than 100 articles cited at least 100 times. Among his honors are the Society for Clinical and Translational Science’s Distinguished Investigator Award, the American Academy of Neurology’s Irwin Schatz Award in Autonomic Disorders, and the NIH’s Distinguished Clinical Teacher Award. Three of his most important discoveries are sympathoadrenal imbalance before neurocardiogenic syncope, cardiac sympathetic denervation in Parkinson’s disease, and the “sick-but-not-dead” phenomenon in neurodegenerative disorders involving catecholaminergic neurons. His single-authored e-textbook, Principles of Autonomic Medicine, is a unique resource available for free download from his NINDS webpage.