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Arthur McCullough

Arthur J. McCullough MD

Professor of Medicine, Lerner College of Medicine, Case Western University; Director of Research, Digestive Disease Institute, Department of Gastroenterology & Hepatology, Cleveland Clinic Foundation, Cleveland, Ohio

Dr. Arthur J McCullough is the Borra Endowed Professor of Medicine at the Lerner College of Medicine at Case Western University. He also currently serves as Director of Research for the Digestive Disease Institute within the Department of a Gastroenterology and Hepatology at the Cleveland Clinic Foundation in Ohio.  He has held multiple leadership appointments including being chief medical resident at the Cleveland clinic (1976-77), director of Gastroenterology at MetroHealth Medical Center in Cleveland (1991-2006), chairman of Department of Gastroenterology at the Cleveland Clinic (2006-2010) and past president (2008) of the American Association of the Study of Liver Disease (AASLD). Dr. McCullough received the Clinician, Educator, and Mentor Award from the AASLD in 2013 and has also received the outstanding teacher award at Case Western University. He has been recognized with the Best Doctor's in America award. Besides his busy clinical commitments, he also has extensive experience in medical research; having conducted multiple NIH funded research studies. Dr. McCullough has had a continuously funded lab for 30 years. His major interest is in metabolic liver disease; particular alcoholic and nonalcoholic fatty liver disease (NAFLD).  He is currently funded as part of the Non-alcoholic Steatohepatitis Clinical Research Network (NASH CRN) where he has served as co-chair of the steering committee and continues to co-chair the Ancillary studies committee of the NASH network. Among his landmark work in NAFLD was the establishment of the current nomenclature used in NAFLD, and he was among the first to show correlation of liver histopathology of NAFLD to clinical outcomes, importance of diabetes in development of NASH cirrhosis and diagnostic biomarkers for NASH. He is also currently funded as part of the Alcoholic Hepatitis UO1, which is investigating novel therapies of alcoholic hepatitis. He has authored more than 150 peer reviewed original articles and over more than 65 editorials and book chapters. He has served on several editorial boards of prominent gastroenterology journals, including Hepatology as an associate editor. Most recently he served as a co-editor for the second edition of “Nonalcoholic Fatty Liver: A Practical Guide”, which is the only textbook devoted solely to the topic of Nonalcoholic Fatty Liver. 

Recent Contributions to PracticeUpdate:

  1. MY APPROACH to the Patient With NASH