Alexander Khoruts MDProfessor of Medicine; Director, Luminal Gastroenterology Section, Center for Immunology, BioTechnology Institute, University of Minnesota, Minneapolis, Minnesota
Dr. Khoruts is the Director of the University of Minnesota Microbiota Therapeutics Program, a multidisciplinary program that brings together clinical and basic science expertise and has been a major leader in the field of intestinal microbiota transplantation (IMT). His group was the first to demonstrate engraftment of donor distal gut microbial communities into recipients suffering from multiply recurrent C. difficile infection and to develope the standardized protocols for donor selection as well as preparation/cryo- and lyo-preservation of microbiota. The program continues to focus its efforts on the pharmacology and mechanistic aspects of this new frontier of therapeutics development.
DisclosuresDr. Khoruts has patents for preparation of microbiota for transplantation and research funding from Finch Therapeutics.
Recent Contributions to PracticeUpdate:
- Temporal Gut Microbial Changes Predict Recurrent Clostridiodes difficile Infection
- Fecal Microbiota Transplant in Real-World Practice
- Bacteriophage Transfer Associated With Fecal Transplant Success in Treatment of Clostridium difficile Infection
- Multidonor Intensive Fecal Microbiota Transplantation for Active Ulcerative Colitis
- High Risk of Post-Infectious IBS in Patients With Clostridium difficile Infection
- Recurrence of C. difficile Infection in Patients With IBD